General Information

  • ID:  hor002944
  • Uniprot ID:  P85799
  • Protein name:  Brain peptide SQAYDPYSNAAQFQLSSQSRGYPYQHRLVY
  • Gene name:  NA
  • Organism:  Apis mellifera (Honeybee)
  • Family:  NA
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Apis (genus), Apini (tribe), Apinae (subfamily), Apidae (family), Apoidea (superfamily), Aculeata (infraorder), Apocrita (suborder), Hymenoptera (order), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  GO:0005576 extracellular region

Sequence Information

  • Sequence:  SQAYDPYSNAAQFQLSSQSRGYPYQHRLVY
  • Length:  30
  • Propeptide:  MMCDWVWLLLTLCSLLMIVQSLPTNLAEDTKKTEQTMRPKSKRAQEMLMFGNQQNHQPENNPSSSYSSTAEKRTLAASGLGGLKAALIEEEKPSRSNTLNNAFYDRKNYDYGAVNELGYEIPQVWDNSPYSRYYTNEDRRKRSEKSAVASGSSTTIKPSTTSFQSPTSTQQSVQTQVKRNVPIYQEPRFKRELDIDPEDVLTLLSLWENERRKRNWHKYMNEEYENVDDEDNLLEEEDSRNIIPWMDSSVYPPRHYSLDSLSPSDIGIIRTHPSSYYEQYENQYGQQYDTSQYGSPQYGLVYPQQTYYSAPEKRFMISRKRSQAYDPYSNAAQFQLSSQSRGYPYQHRLVY
  • Signal peptide:  MMCDWVWLLLTLCSLLMIVQS
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-P85799-F1(AlphaFold_DB_ID)

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor002944_AF2.pdbhor002944_ESM.pdb

Physical Information

Mass: 404323 Formula: C158H226N44O49
Absent amino acids: CEIKMTW Common amino acids: QSY
pI: 8.93 Basic residues: 3
Polar residues: 12 Hydrophobic residues: 7
Hydrophobicity: -102.67 Boman Index: -7203
Half-Life: 1.9 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 45.67
Instability Index: 5131.33 Extinction Coefficient cystines: 7450
Absorbance 280nm: 256.9

Literature

  • PubMed ID:  19576913
  • Title:  Mass Spectrometric Profiling of (Neuro)-Peptides in the Worker Honeybee, Apis Mellifera.
  • PubMed ID:  17068263
  • Title:  From the Genome to the Proteome: Uncovering Peptides in the Apis Brain